ea0014p544 | (1) | ECE2007
Trofimiuk Malgorzata
, Adamek Dariusz
, Czepko Ryszard
, Sokolowski Grzegorz
, Huszno Bohdan
Introduction: Topoisomerase II alpha is regarded as the important marker of cellular proliferation. Pituitary tumours are usually benign, but some of them are characterized by rapid growth, high recurrence rate and local invasiveness. Proliferation marker Ki-67 most commonly used in pituitary tumours is not entirely reliable as the indicator of the aggressive growth of the lesion. Topoisomerase II alpha expression assessment may be a valuable tool for identification such pitui...